Geeske  van Woerden

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Dr. Geeske van Woerden (GM)

Publications

Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome.

in Frontiers in cellular neuroscience
Wang T, van Woerden GM, Elgersma Y, Borst JGG
DOI: 10.3389/fncel.2017.00418

A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel mutants.

in Molecular autism
Sonzogni M, Wallaard I, Santos SS, Kingma J, du Mee D, van Woerden GM, Elgersma Y
DOI: 10.1186/s13229-018-0231-7

Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability.

in Nature communications
Reijnders MRF, Kousi M, van Woerden GM, Klein M, Bralten J, Mancini GMS, van Essen T, Proietti-Onori M, Smeets EEJ, van Gastel M, Stegmann APA, Stevens SJC, Lelieveld SH, Gilissen C, Pfundt R, Tan PL, Kleefstra T, Franke B, Elgersma Y, Katsanis N, Brunner HG
DOI: 10.1038/s41467-017-00933-6

Ub3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice.

in Journal of neurophysiology
Wallace ML, van Woerden GM, Elgersma Y, Smith SL, Philpot BD
DOI: 10.1152/jn.00618.2016

Impaired Neurite Contact Guidance in Ubiquitin Ligase E3a (Ube3a)-Deficient Hippocampal Neurons on Nanostructured Substrates.

in Advanced healthcare materials
Tonazzini I, Meucci S, Van Woerden GM, Elgersma Y, Cecchini M
DOI: 10.1002/adhm.201500815

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

in Neuron
Judson, M. C., Wallace, M. L., Sidorov, M. S., Burette, A. C., Gu, B., van Woerden, G. M., King, I. F., Han, J. E., Zylka, M. J., Elgersma, Y., Weinberg, R. J. and Philpot, B. D.

The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion

in Scientific Reports
Kool, M. J., Van De Bree, J. E., Bodde, H. E., Elgersma, Y. and Van Woerden, G. M.

Neurofibromin regulates HCN activity in Parvalbumin-positive interneurons.

in Molecular psychiatry
Omrani A, van Woerden GM, Elgersma Y
DOI: 10.1038/mp.2015.154

An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression.

in Human molecular genetics
Bruinsma CF, Savelberg SM, Kool MJ, Jolfaei MA, Van Woerden GM, Baarends WM, Elgersma Y
DOI: 10.1093/hmg/ddv436

HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1.

in Molecular psychiatry
Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y
DOI: 10.1038/mp.2015.48
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