Ype  Elgersma

contact

  • y.elgersma@erasmusmc.nl
  • +31 (0)10 7043337
  • +31 010 7044734
  • Room: Ee1438a
  • Dr. Molewaterplein 40, NL-3015 GE Rotterdam

Prof.Dr. Ype Elgersma (Y)

Publications

Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome.

in Frontiers in cellular neuroscience
Wang T, van Woerden GM, Elgersma Y, Borst JGG
DOI: 10.3389/fncel.2017.00418

Autism Spectrum Disorder in an Unselected Cohort of Children with Neurofibromatosis Type 1 (NF1).

in Journal of autism and developmental disorders
Eijk S, Mous SE, Dieleman GC, Dierckx B, Rietman AB, de Nijs PFA, Ten Hoopen LW, van Minkelen R, Elgersma Y, Catsman-Berrevoets CE, Oostenbrink R, Legerstee JS
DOI: 10.1007/s10803-018-3478-0

Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.

in Molecular psychiatry
de Vrij FM, Bouwkamp CG, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, Gopalakrishna S, Ghazvini M, Li TM, Quadri M, Olgiati S, Breedveld GJ, Coesmans M, Mientjes E, de Wit T, Verheijen FW, Beverloo HB, Cohen D, Kok RM, Bakker PR, Nijburg A, Spijker AT, Haffmans PMJ, Hoencamp E, Bergink V, Vorstman JA, Wu T, Olde Loohuis LM, Amin N, Langen CD, Hofman A, Hoogendijk WJ, van Duijn CM, Ikram MA, Vernooij MW, Tiemeier H, Uitterlinden AG, Elgersma Y, Distel B, Gribnau J, White T, Bonifati V, Kushner SA
DOI: 10.1038/s41380-017-0004-2

A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel mutants.

in Molecular autism
Sonzogni M, Wallaard I, Santos SS, Kingma J, du Mee D, van Woerden GM, Elgersma Y
DOI: 10.1186/s13229-018-0231-7

The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function

in Hum Mutat
Proietti Onori M, Koopal B, Everman DB, Worthington JD, Jones JR, Ploeg MA, Mientjes E, van Bon BW, Kleefstra T, Schulman H, Kushner SA, Küry S, Elgersma Y, van Woerden GM
DOI: 10.1002/humu.23647

Adult Ube3a Gene Reinstatement Restores the Electrophysiological Deficits of Prefrontal Cortex Layer 5 Neurons in a Mouse Model of Angelman Syndrome

Improvement of ubiquitylation site detection by Orbitrap mass spectrometry

in J Proteomics
van der Wal L, Bezstarosti K, Sap KA, Dekkers DHW, Rijkers E, Mientjes E, Elgersma Y, Demmers JAA
DOI: 10.1016/j.jprot.2017.10.014

Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability.

in Nature communications
Reijnders MRF, Kousi M, van Woerden GM, Klein M, Bralten J, Mancini GMS, van Essen T, Proietti-Onori M, Smeets EEJ, van Gastel M, Stegmann APA, Stevens SJC, Lelieveld SH, Gilissen C, Pfundt R, Tan PL, Kleefstra T, Franke B, Elgersma Y, Katsanis N, Brunner HG
DOI: 10.1038/s41467-017-00933-6

A brain proteomic investigation of rapamycin effects in the mouse model.

in Molecular autism
Wesseling H, Elgersma Y, Bahn S
DOI: 10.1186/s13229-017-0151-y

Ub3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice.

in Journal of neurophysiology
Wallace ML, van Woerden GM, Elgersma Y, Smith SL, Philpot BD
DOI: 10.1152/jn.00618.2016
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