lab

Neural networks underlying behavioral flexibility

Lab Members

Aleksandra Badura
Dr. Aleksandra Badura
Assistant Professor
Lab Head
Amy Hassett
Amy Hassett
Master Student
Yawende Landbrug
Yawende Landbrug
Master Student
Maria Roa Oyaga
Maria Roa Oyaga
Master Student
Roxanne ter Haar
Roxanne ter Haar
Research Analyst

Recent Publications

Normal cognitive and social development require posterior cerebellar activity

Badura A., Verpeut J.L., Metzger J.W, Pereira T.D, Pisano T.J., Deverett B., Bakshinskaya D.E., Wang S.S.-H
in eLife 2018

Cerebellar Granule Cells: Dense, Rich and Evolving Representations.

Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning.

Giovannucci A, Badura A, Deverett B, Najafi F, Pereira TD, Gao Z, Ozden I, Kloth AD, Pnevmatikakis E, Paninski L, De Zeeuw CI, Medina JF, Wang SS
in Nature neuroscience 2017

Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

in Scientific reports 2016

Cerebellar associative sensory learning defects in five mouse autism models.

Kloth A.D., Badura A., Li A., Cherskov A., Connolly S.G., Giovannucci A., Bangash M.A., Grasselli G., Peñagarikano O., Piochon C., Tsai P.T, Geschwind D.H., Hansel C., Sahin M., Takumi T, Worley P.F.,Wang S.S.-H
in eLife 2015

A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice.

Clopath C, Badura A, De Zeeuw CI, Brunel N
in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014

A cerebellar learning model of Vestibulo-Ocular Reflex adaptation in wild-type and mutant mice

Clopath, C., Badura, A., De Zeeuw, C. I. and Brunel, N.
in Journal of Neuroscience 2014

Climbing fiber input shapes reciprocity of Purkinje cell firing.

Badura A, Schonewille M, Voges K, Galliano E, Renier N, Gao Z, Witter L, Hoebeek FE, Chédotal A, De Zeeuw CI
in Neuron 2013

Purkinje cell-specific knockout of the protein phosphatase PP2B impairs potentiation and cerebellar motor learning.

Schonewille M, Belmeguenai A, Koekkoek SK, Houtman SH, Boele HJ, van Beugen BJ, Gao Z, Badura A, Ohtsuki G, Amerika WE, Hosy E, Hoebeek FE, Elgersma Y, Hansel C, De Zeeuw CI
in Neuron 2010

Genetic dissection of the function of hindbrain axonal commissures

Renier N, Schonewille M, Giraudet F, Badura A, Tessier-Lavigne M, Avan P, De Zeeuw CI, Chédotal A
in PLoS Biol 2010

Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning

Wulff P, Schonewille M, Renzi M, Viltono L, Sassoè-Pognetto M, Badura A, Gao Z, Hoebeek FE, van Dorp S, Wisden W, Farrant M, De Zeeuw CI
in Nature neuroscience 2009
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